Asking a focused clinical question using the pneumonic PICO (T) as it is a helpful approach to summarizing the literature that explores the effect of a specific therapy.
P=Patient, Population or Problem
Scenario: I am a nurse working in the pediatrics day hospital and I have been asked to search for the best evidence on interventions like distractions for easing children's fears of needles during immunization.
PICO Question: In the pediatric population, do distraction techniques during immunization result in less pain and anxiety?
A research question should be clear and focused, where you can then draw upon multiple sources to present your argument.
Scenario: I am working with a colleague on submitting an NIH grant to explore the cancer-obesity link and need assistance with a literature search on the following topic: while obese people are at a higher risk for developing cancer, have worse prognoses and may be resistant to chemotherapy, we would like to know why.
Research Question: How does obesity promote tumor development?