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DATE: February 15, 2024
TO: Hospitals, Local Health Departments, Laboratories, Emergency Rooms, Family Medicine, Pediatrics, Adolescent Medicine, Internal Medicine, Infectious Disease, Infection Control Practitioners, and Primary Care Providers
FROM: New York State Department of Health Division of Vaccine Excellence
The New York State Department of Health is forwarding a communication issued by the Centers for Disease Control and Prevention to share information about the following:
Measles typically presents in adults and children as an acute viral illness characterized by fever and generalized maculopapular rash. Signs and symptoms appear 7 to 21 days after initial exposure.
The prodrome may include cough, coryza, and conjunctivitis. The rash usually starts on the face, proceeds down the body, and may include the palms and soles. The rash initially appears discrete but may become confluent and lasts several days.
Symptoms may be mild, absent, or atypical in persons who have some degree of immunity to measles virus before infection (e.g., in previously vaccinated persons).
Serious side effects of measles can include pneumonia, encephalitis, hospitalization, and death.
Suspected measles cases must be reported immediately to the local health department of the patient’s residence. The local health department in New York State (outside of New York City) can assist in arranging testing at the Wadsworth Center Laboratory, and for specimens to arrive at the lab within 24-hours of collection, when feasible.
Follow Wadsworth Center Laboratory’s tip sheet and collect either a nasopharyngeal swab or throat swab for reverse transcription polymerase chain reaction (RT-PCR), as well as a blood specimen for serology, from patients with suspected measles for testing at the lab. Urine may also contain virus so collect a urine sample in addition when feasible. Follow the packaging and shipping instructions on the tip sheet. However, if sending serology only, address to: Diagnostic Immunology Laboratory at David Axelrod Institute Wadsworth, 120 New Scotland Ave, Albany, NY 12208.
Those who are infected should be isolated for four days after they develop a rash; standard and airborne precautions should be followed in healthcare settings. People who are suspected to be exposed to measles who cannot readily show that they have evidence of immunity against measles should be offered post-exposure prophylaxis (PEP).
To potentially provide protection or modify the clinical course of disease among susceptible persons, either administer MMR vaccine within 72 hours of initial measles exposure, or immunoglobulin (IG) within six days of exposure. Do not administer MMR vaccine and IG simultaneously, as this practice invalidates the vaccine.
This report is based on data as of January 1, 2024 from the New York State Immunization Information System (NYSIIS). The rates below are calculated based on data of children who have received 1 MMR (Measles, Mumps, Rubella) immunization by 2 years of age, reported their residency as the State of New York, provided their New York State county of residence, and have at least one immunization or have a New York State birth record outside of New York City. According to CDC, children should receive the first dose of MMR vaccine routinely at age 12 through 15 months of age.